The binding of the retro-analogue of glutathione disulfide to glutathione reductase.
نویسندگان
چکیده
The retro-analogue of glutathione disulfide was bound to the GSSG binding site of crystalline glutathione reductase. The binding mode revealed why the analogue is a very poor substrate in enzyme catalysis. The observed binding mode difference between natural substrate and retro-analogue is explained.
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 265 18 شماره
صفحات -
تاریخ انتشار 1990